Chronic Disease: Infectious Cause?

Iron Localization and Infectious Disease in Chronic Kidney Disease Patients.

For patients on dialysis, infection is the second leading cause of mortality. Iron metabolism should be considered in the pathogenesis of infectious disease, as high local iron concentrations favor the growth of many microbes. This review is intended to provide information regarding iron metabolism and infection in chronic kidney disease (CKD) patients. There are 2 reasons these patients may be...

Rheumatic heart disease: infectious disease origin, chronic care approach

BACKGROUND Rheumatic heart disease (RHD) is a chronic cardiac condition with an infectious aetiology, causing high disease burden in low-income settings. Affected individuals are young and associated morbidity is high. However, RHD is relatively neglected due to the populations involved and its lower incidence relative to other heart diseases. METHODS AND RESULTS In this narrative review, we ...

karyomegalic tubulointerstitial nephritis: a rare cause of chronic kidney disease

How infectious agents cause cancer

Dalton-Griffin and Kellam: Journal of Biology 2009, 8:67 Abstract Molecular techniques for identifying pathogens associated with cancer continue to be developed, including one reported recently in BMC Medical Genomics. Identifying a causal infectious agent helps in understanding the biology of these cancers and can lead ultimately to the development of antimicrobial drugs and vaccines for their...

Genetic Mutations that Cause Coronary Artery Disease